Talk the chemistry treatment of malignant and lymphoid lump

The malignant and lymphoid lump is the malignant tumor of lymphoid cell origins, be so called a lymphoid cancer, can take place in each part of whole body, because of lymphoid cell origins different and pathologic organization classification dissimilarity, to the reaction of treatment and also have very big difference as a result.From the past till now the clinical doctor and pathologic doctors had been make great effort of looked for various classification method, and searched to have something to do with treatment effect of prepare behind factor with provide more likely treatment way.This text will to the malignant and lymphoid lump of different type accept what chemistry medicine treatment and its treatment result are explain as follows respectively:



A, the surname disease(He2 Jie2 Jin's surname lymphoid lump) its treatment of He2 Jie2 Jin:



The treatment method of the surname disease of He2 Jie2 Jin with it prepare behind is clinical with it to expect don't and have have no the dangerous factor have relativity.The dangerous factor of the surname disease of He2 Jie2 Jin includes the chest Zong Ge swollen lymphatic gland inside the chamber exceed chest Kuo 1/3 of diameter, lymphatic gland outside of disease, the spleen is subjected to invasion, and more than three lymphatic gland parts be infringe upon etc..If the patient is clinical up Issue 1 or 2s but have no dangerous factor existence, then can project a line irradiation treatment, its livability of five years reaches to 95%.If the in danger factor exist then can consider is cure with ABVD chemistry medicine two after treating a distance, and project a treatment to increase curative effect.



When the patient is clinical up Issue 1 or 2 and has more than an and dangerous factor, or clinical top Issue 3 but have no dangerous factor, its treatment method needs to include four MOPP(COPP) and ABVD chemistry medicine which treat a distance treatment and projects gland to project light upon a treatment, by this treatment result, its livability of five years can reach to 80%.When the patient is a later period to more discover such as Issue 3 combine the patient of in danger factor or Issue 4, then need to accept 6-8 chemistry treatment of the MOPP-ABVD which treat a distances.When the patient accepts a standard treatment after, can't get to alleviate to get disease to again deliver, need to be consider the chemistry of the second line treatment or Gao Ji4 Liang2 chemistry treatment and from body peripheral blood stem cell transplant, be used as rescue to cure.When the patient acquires to survive over a long period of time after accept the treatment, probably cause the second malignant tumor because of once accepting chemistry medicine, press covariance data to have .2 after cure 3-10 years%of patient creation type marrow leukemia, have around 77 － 86% patients have already grown function not whole problems.



Two, not He2 Jie2 Jin's surname lymphoid lump of cure



Not He2 Jie2 Jin's surname lymphoid lump from the malignant tumor of the B lymphoid ball or the T lymphoid ball origins, because of the cell type, pathology organization type and other prepare behind factor dissimilarity, will choose a different treatment method, the result of its treatment has already will have difference.



Not the He2 Jie2 Jin's surname lymphoid lump after prepare its dissimilarity can is divided into a low and malignant degree, medium malignant degree and high and malignant degree not He2 Jie2 Jin's surname lymphoid lump.



A.low and malignant degree not He2 Jie2 Jin's surname lymphoid lump:



Include the small lymphoid lump valid chemistry medicine contains cyclophosphamide, chlorambucil, prednisolone and fludarabine, average general patient survival period invite is 6-8 years, it the livability of 10 years is about 40%, to knot the stanza cellule lymphoid lump first or the second period patient can use the treatment that the whole lymphatic glandses project light upon, to Issue 3 or four expect the patient can then consider with delay a treatment, project treatment, single chemistry medicine treatment and from the treatment of body marrow transplantation, the doctor will aim at each patient probably because of what treatment acquire the biggest advantage but choose adequacy a treatment method.Expect the patient's treatment to then adopt to the knot stanza big cell lymphoid lump the 1 and 2th four treat the CHOP chemistry of distance medicine a treatment and project a treatment, can make 84 acquire to survive over a long period of time to 90% patients.Knot stanza big cell a lymphoid lump patient usage CHOP to Issue 3 or 4 or other the chemistry medicine strengthen treatment, 5 year livability is 58%.



B.medium malignant degree not He2 Jie2 Jin's surname lymphoid lump:



Mainly with fill the air sex greatly lymphoid cell lymphoid lump is lord, expect the patient to accept CHOP chemistry medicine a treatment or plus to project a treatment to the 1 and 2th, it 4 year, the livability can reach to 73% and accept CHOP chemistry medicine a treatment to Issue 3 and 4 three years are after it of disease free survival rate is about 41%.



C.high and malignant degree not He2 Jie2 Jin's surname lymphoid lump:



Can adopt the chemistry treatment that traditional medicine treatment of the CHOP chemistry or various chemistry medicine combine, it 2 years without disease livability at the third period patient for about 61 － 92% at the fourth period patient appoint to don't wait to 87% from 17%.Then adopt the treatment method of similar impatient lymphatic leukemia to the treatment of lymphoid bud ball lymphoid lump, it 3 years it is 58%s for about 53% －s without the disease livability.



The chemistry treatment is a count for much and valid treatment method to the lymphoid lump patient, but the chemistry medicine cure to also probably produce to vomit, disgusted, bald-headed, the leukocyte decrease, infection, mouth cavity ulcer etc. side effect, may also cause the side effect of heart toxicity.Has 5% patients around and may endanger life because of accepting a chemistry treatment according to the estimate.



In fine, the malignant and lymphoid lump includes various cell type, pathology organization type and clinical prepare behind a flock of malignant and lymphoid tumor of factor dissimilarity, the doctor need clear what patient contract is which category of lymphoid lump, consider it age, healthy physique condition, heart lung function...etc., again decide to adopt what chemistry medicine treatment.Need side effect of notice its creation in the meantime, make the patient acquire the best curative effect.