Recently, the researcher of American hero Fei in Philadelphia, lousy medical college and Kimmel cancer center discover that the zinc can have already helped esophagus and mouth cavity cancer of prevent°from the high Wei individual.Mouth cavity and esophagus cancer have something to do with nourishment zinc lack, and the Mao COX-2 ascension of expression also mutually contact with these cancers.The Louise Fong wait for someone to discover that letting the big rat of lack the zinc take orally zinc can repress a develop of esophagus and the mouth cavity ex- cancer form and still lowered the expression level of COX-2 in the meantime.
These detections express that the complement of zinc may prevent°from the development of esophagus or mouth cavity cancer, these cancers lack in the zinc of the developing country be an outstanding problem.The researcher announce these detections are on the Cancer Institute of the National of the Journal of in January 5, 2005.
The zinc that the mankind absorb usually comes from red meat and seafood article.However, lack zinc about the food of 10% Americans, but then have about 2,000,000,000 people to lack zinc in the developing country.The Epidemiology studies the enunciation recent some years, esophagus and the mouth cavity cancer outbreak rate to be placed in to continuously rise of trend.And, about there are 13000 Americans dying in esophagus and mouth cavity cancer annually.
The Fong Doctor has been concentrate on to study zinc to lack cancerous with esophagus with it of contact, and set up zinc to lack with the animal model of the cancer sensitivity.The zinc lacks the cell that will increase esophagus and mouth cavity to expand and make thus these districts are to the carcinogen sensitive, so increased the risk of cancer development.
The Fong Doctor lacked esophagus and tongue of big rat to organize medium egg whites COX-2s and gene to express a circumstance to carry on a comparison to the normally big rat and the zinc.They discover that the zinc lacked the COX-2 expression level of big rat to increase 10-1500%.The cell expand the level also increases in the meantime.After letting to lack the zinc big rat to take zinc, the expression of COX-2 shows Zhao to lower and the ex- cancer cell propagated to also take place to converse.The researcher also discovers to use depressant COX-2 the big rat of the processing, it COX-2 and cell propagated levels to all descend.
Experimented a certificate a zinc treatment to recover many systems being lack by zinc to influence.Connect down, the researcher return will investigate zinc and low quantity of celcoxib(the living creature note:Depressants COX-2)unite usage's prevention effect for digest way cancer.
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