Make progress of the urine bladder cancer chemistry treatment

The urine bladder cancer is one of the familiar tumor of the Bi urine system, only next to prostate gland cancer.Among them shallow have 75~80% in the type, the rest is an invasion type and even the disease has already assignor happenned.The organization type of the most familiar pathology for move the form top skin cell a cancer.Take place at the old people mostly.The so-called chemistry treatment means to make use of medicine to kill a kind of method of cancer cell.Chemistry treatment's role in the urine bladder cancer include:1, shallow infuse to wash at type the chemistry medicine of the urine bladder cancer(Issue 0, the AN expect);2, transfer an urine bladder cancer:( The D2 expect)of alleviate a sex chemistry treatment;3, invasion type urine bladder cancer:( The B, C, D1 expect)before the Shu or after the Shu of the chemistry treatment of assistance;4, the invasion type's urine bladder cancer's merger project and the chemistry cure.(the urine bladder reserve therapy)



1, shallow infuse to wash at type the medicine of the urine bladder cancer



Medicine inside the urine bladder's infusing to note is led an urine tube by 1 to infuse for the book the anti-cancer medicine is through the urethra into urine bladder inside, stop over a period of time, hope to kill the cancer cell that the not yet finished all cuts off to wish an exaltation treatment a rate.Apply the object as the urine bladder cancer of form shallow(infringed upon to the muscle layer).The form shallow sex urine bladder cancer have three, 40% in order to deliver sex more, is alone cut off tumor by urine bladder mirror is not enough, it again the hair rate is up to 75% ～s 80%.Even having 10% ～s 15% will make progress into an invasion type.So form shallow sex urine bladder the standard treatment of the cancer should include:The urine bladder mirror merges after cut off tumor and Shu medicine inside the urine bladder infuse to note.Medicine inside the urine bladder infuses to note of purpose is:Exterminate existent urine bladder tumor and prevent°from the urine bladder tumor deliver again, and prevent°from the urine bladder tumor make progress into an invasion type.Doxorubicin, Epirubicin and Mitomycin in common usely infuse to note chemistry medicine.On the cultural heritage suggested to just finish do an urine bladder mirror tumor to cut off soon, then started infuse to note chemistry medicine's effect the best.To expect to count Gao, pathology organization of divide poor or the home position cancer prepare behind worse, then can convert into BCG(bcg vaccine) to infuse to wash the best.The BCG belongs to immunity medicine, is confirm most effectively.It to prevention urine bladder tumor again hair or invasion all helpful, but part of side effect more big, some people can't is tolerant of.Also have after two chemistry medicine infuse note, some patients continue to dispense continuously for 6 weeks, the chemistry medicine infuses to wash, after again continuously for 10 months 4 weeks 1 time chemistry medicine infuse to wash.Chemistry medicine inside the urine bladder infuses the weakness for note as curative effect time be brief, decrease again hair rate only 10~15%, and have no help towards preventing urine bladder tumor from make progress into an invasion type.The side effect infused to wash most familiarly stimulates symptom for the urine bladder.Track the first year to do an urine bladder mirror check and urinate cancer cell a check in the urology inside beard each 3 months, the second year and is every half year once the third years.After the form shallow sex urine bladder prepare of cancer with expect count and organization of divide relevant.The form shallow sex urine bladder tumor cures behind if relapse and then terminate to infuse a medicine to go the urine bladder mirror excision tumor again.Such as still is a form shallow sex urine bladder tumor, in the tumor cut off after, can continue chemistry medicine inside the urine bladder infuse to note.Such as still is a form shallow sex urine bladder tumor, but expect to count to increase Gao or pathology divide degree to become bad, it prepare worse behind.Such as change in order to infringe upon to the urine bladder tumor of muscle layer, chemistry medicine inside the urine bladder infuses to note invalid.The cultural heritage has already reported new Gemcitabine(the Jian choose) of the chemistry medicine to may also go to infuse to note inside urine bladder recently, there is the potential of development.Infuse to note chemistry medicine to add a heat treatment(hyperthemia) inside urine bladder also is confirm to can increase curative effect.



2, transfer the sex chemistry treatment of alleviate of an urine bladder cancer



In the past Bi urethra cancer the most famous merger chemotherapy was a MVAC(Methotrexate, Vinblastin, Doxorubicin, Cisplatin), although the effect was good(the clinical reaction rate was 39~65%), the toxicity was big(the marrow repress, kidney toxicity and easy germ infection) and have already less used now.New medicine the Gemcitabine(the Jian choose) and the Paclitaxel(Pacific Ocean yew Chun) be the most valid.The Gemcitabine health insurance has already can be pay in the urine bladder cancer of later period a patient;If use alone, can make 27% sufferer have a clinical reaction rate(the tumor contract more than 50%), if merge with platinum compound to use, then equally can survive for 12-14 months.The Paclitaxel(Pacific Ocean yew Chun) health insurance hasn't pay.GP(gemcita bine, Cisplatin) and TP(Paclitaxel, Cisplatin) effect are good(the clinical reaction rate distinguish to 57~66% and 62~72%) and the toxicity is small.The new medicine is small for new medicine toxicity with the comparison of old medicine, need not excrete from the kidney, clinical completely reaction rate older medicine Gao.Chang Gung hospital in Linkao uses FLP(5 ～ Fluorouracil, Leucovorins, Cisplatin) to cure a Bi urethra cancer, the effect is as well good(internal data:The clinical reaction rate is 50%, the livability is 8 months), the toxicity is small, quality of life good.The chemistry treatment isn't doesing move form top skin cell cancer, internal organs assignor and the physique not good, curative effect not more good).



3, invasion type urine bladder cancer before the Shu or the assistance chemistry of the empress of the Shu cure



The chemistry treatment of assistance can use before surgical operation or after operation can also merge to project a line treatment.Exterminate sex urine bladder cut off(radical cystectomy) behind the object of scholar of being the chemistry treatment is high cancer again hair or assignor, include the tumor has already spread out the outside of the urine bladder or has already infringe upon to close by the organizer, pelvis chamber have already have there is lymph or blood vessel on the lymphatic gland assignor, or pathology infringe upon.Chang Gung hospital in Linkao uses a chemistry treatment FLP each 3~4 Monday time total 6 merger project the line cure 5000 thunders virtuous to cure these a high and dangerous cluster a patient.



The chemistry cures before the Shu of advantage in order to can make the tumor contract, make at first hard make urine bladder excision can go excision again.The weakness is a chemistry treatment toxicity big, have no help to the livability.The sufferer is cut off tumor to go a chemistry treatment again by urine bladder mirror first, compare the one who haven't yet to cut off tumor to go a chemistry treatment from the urine bladder mirror, clinical completely the reaction rate be higher.



4, the invasion type's urine bladder cancer's merger project and the chemistry cure(the urine bladder reserve therapy)



For isn't suitable for to have operation and don't want that the invasion type urine bladder cancer had operation or can'ted have operation can consider this method.Basically and first Be cut off tumor by urine bladder mirror, again the merger project and the chemistry cure to reserve urine bladder.If the cancer disease still continuously exists and can carry on again to exterminate sex urine bladder to cut off.The ideal condition include:Tumor compare the small, urine bladder mirror can completely cut off a tumor, have no kidney dropsy, and merger emanation and inflorescence treatment can reach a complete reaction.Chemistry treatment's using the FP(5 ～ Fluorouracils, Cisplatin) merger emanation line a treatment is a recent in common use therapy.The patient has around after cure six, the patient of 70% can reserve urine bladder.The livability for three years can reach to six to 80%.Clinical completely respond, the most may also attains a pathology to completely respond.The therapy's toxicity is as well small and diminish such as the radio enteritis or the urine bladder capacity etc., greatly the part can is tolerant of.Aim at an invasion type urine bladder cancer, Chang Gung hospital in Linkao uses a chemistry treatment FLP:5 ～ Fluorouracil, Leucovorins, Cisplatin)each 3 － 4 weeks is an expect to be total 6 expect to merge to project line to cure 6000 －s 6400 thunders virtuous to reserve urine bladder.Although patient's ising greatly part of is old man's house, the side effect be little.The livability for three years reaches to 69% and have no livability that tumor deliver again to reach to 65% for three years.



5, conclusion



Cure the urine bladder cancer must section border the cooperation of.The chemistry treatment is regardless shallow in the urine bladder cancer in the type, invasion type and transfer a sexual urine bladder cancer to all have it the important position role.Shallow infuse to wash to the prevention tumor with the chemistry medicine at the type urine bladder cancer of then the hair has a help.The invasion type urine bladder cancer can choose a high and dangerous cluster a patient, chemistry treatment of do the assistance after exterminating sex urine bladder to cut off.To particular patient can the book merger project and the chemistry cure to reserve urine bladder.Transfer although the urine bladder cancer of type new chemistry treatment medicine such as the Gemcitabine and the Paclitaxel curative effect and the toxicity little, still need to expect better medicine or cure a method to appear to increase curative effect.