Talk about an ancient medicine and say now the medicine ～ talks the hormone treatment of take orally of breast cancer

Substantially, the treatment method of breast cancer can is divided into following two major typeses:(1)The part cure:Make use of surgical operation excision tumor and project a treatment to control tumor partial sex growth.(2)The whole body cure:Make use of treatment or hormone medicine of the chemistry medicine to exterminate and/and repress cancer cell proliferation in the part of human body.



A lot of incitements but growth that the cell of breast cancer is to be subjected to estrogen(estrogen), if cut off of the estrogen in the tumor cell be be subjected to by body(ER) or Yun hormone to realize(PgR) content Gao, hormone treatment will effectively can resist cancer cell with the homologous hormone therapy.Whereas, if the hormone in the tumor cell is subjected to the body content low words, the treatment effect of the hormone worse.This chapter is the lately old hormone medicine which wants for the brief introduction breast cancer of each reader.Wanting what to clarify first first BE, at clinical ask to diagnose, we often say with patient, draw hormone medicine for them, in fact open "hormone depressant".



The estrogen depressant that can choose to use according to the formal suggestion of European and American cancer related organization currently is Tamoxifen and Arimidex or Femera.



(1)Tamoxifen:It is an old medicine, but withstands a horary test.Its ising a book is received a stop of machine by the estrogen, avoid the cell of breast cancer continuing to grow up because of the function of estrogen and it may also lowers to the incidence rate of side breast breast cancer in the meantime.Its function method is different from chemistry treatment and it is directly the growth which represses tumor cell but is to kill tumor cell.The research shows Tamoxifen for have already stop menstruating, ER the women of the masculine gender use a performance tallest.As for before stop menstruating, ER masculine gender of women's sufferer had better then in chemistry treatment be over behind give again to is the prevention of period five years to cure.Moreover take Tamoxifen to compare the patient whom the short date takes Tamoxifen for five years, can reduce breast cancer to relapse and death rate.But didn't take Tamoxifen over five years currently, the curative effect better proof, past generally suggest Tamoxifen a treatment a period for five years.



Greatly part of patients taking Tamoxifen doesn't have obvious side effect, more possible side effect is that the fever is red, disgusted, vomits, the vagina be unwell, the vagina bleed, the weight increment, vein blood bolt and film pathological changes inside the womb.As for the friend of disease care most of the risk of film cancer inside the occurrence womb, may increase 2 －s 700%, but the Tamoxifen is far larger than bad place to the patient's advantage of breast cancer, so don't suggest the patient of breast cancer stops take Tamoxifen, and film pathological changes inside the womb at Taiwan of the incidence rate be away below abroad.But our wanting what to emphasize's being the women who take Tamoxifen should periodically accept a gynecology check annually, and tell a doctor is take Tamoxifen.If there is leading abnormality bleed should even immediately tell the gynecology the doctor.



(2)Fragrant wreath conversion Mao depressant and don't activate at past, use after the Tamoxifen the patient of invalid breast cancer, can use it the second line hormone therapy combine not much, and the curative effect be most likely poor.Several near in the last yearses to Tamoxifen side effect research develop an estrogen depressant of new generation.They main the function which to fragrant wreath conversion Mao creation repress or don't activate, quickly lower the density of estrogen, as a result attain the purpose that the cell of repress breast cancer grow.The medicine which appears on market currently has 3 kinds:1.The 2. Letrozoles of the Anastrozole is can go against of not- solid 3. Exemestanes of Chun aromatase inhibitors then for can't go against of solid inactivator of the Chun aromatase.Their sufferer in invalid breast cancer of the Tamoxifen still emerged excellent curative effect, and the side effect be very small, the large clinical trial has already confirmed Anastrozole or Letrozole used for the sufferer of breast cancer of Tamoxifen failure, its curative effect is oldly and obviously better than the second line hormone product, and the side effect also show Zhao to lower.Their advantages are the side effect which didn't cause the film pathological changes in the womb and probably appear of the side effect is red, disgusted for fever and vomit, lack bone soft etc. of the appetite, headache, Gao Xie3 Zhi disease.



Currently the health insurance norm of the threes homology, belong to new generation the second line to use a medicine.But expert point out, 1 has been already complete and many item under way medium of large clinical trial show, belong to the same a hormone treatment fragrant wreath conversion Mao depressant of the medicine, women's breast cancer relapses after using to prevent°from stop menstruating of the effect be even better than Tamoxifen!Although the Tamoxifen is still seen the standard which cures as the hormone of breast cancer currently,we believe to will use fragrant wreath to convert Mao depressant's conduct and actions to stop menstruating in the future behind the sufferer's forefront assistance of breast cancer cure or the forefront hormone of later period breast cancer cure, is an inevitable trend.



The end still keeps needing to appeal the friend of everyone's disease, if has any problem that must ask specialty doctor, absolutely not to the way listen to incorrectly pass on a mistaken message way say, , as a result lost the opportunity of the treatment.