The year over 50 sincerely defend a prostate gland cancer

The outbreak rate race difference is huge

The prostate gland cancer is one of familiar Bi urine system malignant tumor and its outbreak rate has tremendous difference in of different races and region.At the United States, Canada, Australia etc. nation, the prostate gland cancer is the most familiar malignant tumor of male, take up 1/3 of the male malignant tumor around, the death rate shares the 2nd, only next to lung cancer.The outbreak rate of prostate gland cancer equally has obvious difference in the of different races of the United States, among them black outbreak the rate be the tallest, 2001:American black 225/100,000, white man 145.8/100,000, Spanish descent person 101.6/100,000, descendant in the Pacific Asia region 80.4/100,000, American Indian 45.8/100,000.In Europe of mostly national, prostate gland cancer similarly male the most familiar malignant tumor, its outbreak rate shares the 1st or the 2nd, basis 90's in 20 centuries European part nation of covariance, prostate gland cancer of outbreak rate is 36/100,000~81.9/100,000.Include China, Japan, Korean etc. nation in Asia, the prostate gland cancer outbreak rate is lower.(2.3/100,000~9.8/100,000)The outbreak rate of prostate gland cancer has thus huge difference between the of different races and inherit a factor doubtless is the main factor which influences a prostate gland cancer an outbreak.The research discovers that the Asian person changed residence to prostate gland from the mainland cancerous after the United States of the outbreak rate obviously rises, this occurrence which hints that geography environment and food habitually wait a factor to all influence a prostate gland cancer.

About 20 in the last years prostate gland the outbreak rate of the cancer have very big variety.According to statistics at the beginning of 80's in 20 centuries the prostate gland cancer outbreak rate of the United States about 80/100,000, go to in 1992 the outbreak rate year by year rises to reach to 180/100,000.Since 1994 the prostate gland cancer outbreak rate has to descend.Still have already added case 198100 in 2001 in the United States, have 31% of male malignant tumor, die 31500, have 11% of male malignant tumor.There is obvious up-trend in the outbreak rate of Chinese prostate gland cancer, too, investigates 30 provinces, city, 187 interborough hospitals in the whole country in 1997 result showing that the outbreak rate of prostate gland cancer increase 2~300%.The surgery graduate school of the University of Peking Bi urine 1990, 1995, 2000 and 2001 with the prostate gland cancer in 2002 accept a cure example to distinguish to 18, 24, 68 and 80 with 101.The increment and mankind's life span extension, population advanced age of the outbreak rate turns the publish of antigen(PSA) of the trend, prostate gland particularity, the clinical image learns development and wears to stab to live a check technique an exaltation etc. the diagnosis be technical of improvement related, check to make a prostate gland cancer to look up a rate to show Zhao increment to the 50 years old above male normal regulations PSA Shai.Although the prostate gland cancer outbreak rate increment, the death rate obviously descend, according to statistics from 1990-2000 years the United States is male the death rate be 50~74 years old to descend 1/3, 75~84 years old descend 1/4.The its main reason was in early days to diagnose and the surgical operation cured with valid endocrine in time.Therefore study outbreak reason and impact factor of prostate gland cancer, make sure easy feeling crowd will for valid prevention, diagnose in early days with exaltation the existence rate provide importance basis.

Be taken bad impact factor

There is a great deal of research in the outbreak mechanism of prostate gland cancer, if suppress cancer gene, original cancer gene, various growth factor and tumor to take place related living creature to regulate vegetable etc. of the research elaborated in the prostate gland cancer the occurrence the process to the interaction of different link.Occurrence, development and male hormone of prostate gland cancer are closely related, so influence the male hormone synthesize, activity with at metabolism of the factor(gene) all may influence the occurrence of prostate gland cancer.The research express that the prostate gland cancer outbreak rate the heredity foundation of difference is the difference of gene sequence between the race, namely the gene list check the Mao much sourer Tai.(the polymorphism of the single nuclear, SNP)The relevant male hormone synthesizes the gene of the pit SRD5 A2 of the key Mao CYP17 in the process many Tais, and influences hormone living creature the effect develop of the male hormone is be subjected to by body(AR) and vitamin D the body(VDR) gene many Tais and prostate gland cancer be taken bad the relation of risk is subjected to people's concern day by day.These genes are many the Tai's analysis all has the research report the way in the of different races and the region crowd and it announced to public an of different races male hormone related gene the relation of many Tai difference and the prostate gland cancer outbreak rate differences.

The reason of the huge race difference of the prostate gland cancer outbreak rate, in addition to environment and food habitually wait a factor, inherit the foundation is a main reason.The occurrence of the prostate gland cancer is the complicated process that a many genes participate, the of gene exists interaction with mutually check and supervision.The easy sensitive faculty of prostate gland cancer probably and various genes many Tais be related, and of gene, of many Tais of gene existence catena but unbalance, caused the gene express and the obvious difference of gene function, so judgment prostate gland cancer occurrence the risk should carry on comprehensive analysis to various different genes, much more different Tai.Pass is many Tai researches to the gene, can for the easy feeling crowd of the prostate gland cancer really settle, prostate gland cancer of the prevention provide importance basis, and to prepare behind judge with treatment project of the choice have actual meaning.

Applied the consociation's treatment's curative effect was the best in early days

Put to treat to not only used for to limit sex prostate gland in early days currently cancer of cure for good sex treatment, as well gradual applied make progress the appeasement of sex prostate gland cancer a treatment in later period, the prostate gland cancer cures for good sex excision a postoperative ssistance a treatment and combines with endocrine treatment of consociation treatment.Along with put to treat technical of exaltation and the calculator technical development, excepted the irradiation projects the outside of the treatment, the 3 Ds proper form project treatment, organization's technique which project a treatment also more and morely the application be cancerous at the prostate gland of treatment.

The prostate gland cancer sufferer goes to put to treat after go the prostate gland cure for good sex resection of orientation certificate, generally include after the Shu a pathology to confirm for medium later period pathological changes, have prostate gland to wrap film invasion, seminal vesicles invasion or slice after the good luck masculine gender, Shu the PSA continuously goes up or goes up more than 6 months and has already lived check to confirm of part relapse etc..

The cultural heritage lent support to to put to treat more alone prostate gland to cure for good an excision ability to obviously raise tumor part and don't relapse a rate after report that the Shu, both the control rate with above partial 10 years has already shown Zhao difference, but existence rate and distance transfer a rate have no obvious difference.The Shu put to treat the partial failure rate that can lower to wrap film invasion, seminal vesicles invasion or slice good luck a male sufferer behind, don't the one who use to put to treat puts to treat after distinguishing to 45%, 31% and 25%, but lending support to Shu then is 14%, 4% and 1%.Cure for good PSA to descend the sufferer of failure to carry on put of remediable to treat after sex excision to the prostate gland cancer, its curative effect result is very inconsistent, but generally thinks that the remediable puts to treat to early carry on and compare to carry on late effective, on a certain degree, these went an assistance to put to treat to provide a proof after cure for good sex surgical operation excision for the prostate gland cancer as a result.

Project treatment and endocrine cure of the comprehensive treatment include the curative effect which puts to treat for the sake of the exaltation but carry on of put before treat and put to treat to moderate to put an endocrine treatment after treat, and carry on while curing for good sex to appear to relapse after put treat of endocrine treatment.For put to treat to cure whether consociation treatment can raise the curative effect of prostate gland cancer or not with endocrine, study a result still currently disunity.Relevant consociation treatment of research manifestation, in early days prostate gland cancer application consociation treatment curative effect had better, but another report way think, the simplicity puts to treat a set and puts to treat to add an endocrine treatment, the set relapses a rate, distance to transfer a rate, tumor death rate in the part, have no disease of existence rate's etc. all have no obvious difference, but total the existence rate have obvious difference, the simplicity puts to treat a set for 10 years, existence rate is 47%, but unite the treatment set as 26%.

Recently along with organization the widespread application which put to plant to put to treat, the male hormone stops the consociation which puts to treat of treatment and organization's application more and more, the male hormone stop behind the prostate gland physical volume obviously contracts, but relevant the male hormone stop a treatment and can increase an organization put to treat behind of without lump existence rate of proof insufficiency, and will increase to put to treat cause of impatient urine the road merge disease, and lower a penis erection function.For at outside project light upon a treatment after appear PSA to go up or part relapse, whether should carry on an endocrine treatment, when start, adoption what project the etc.'s problem also didn't unify standpoint currently.