Shallow talk a prostate gland cancer

【All say 】

The prostate gland cancer is one of the main reasonses that the male cancer die in the Europe and America.Outbreak rate with age growth, 80 years old above check prostate gland a half the number to have a cancer focus, but the physically clinical outbreak is away below this number, the prostate gland cancer outbreak contains obvious region and race difference, according to statistics Chinese lowest, the European is the tallest, African and Israeli nations such as mediacy, our country and Japan etc. for prostate gland cancer low hair region, but have never chosen 50 years old bove male corpse check prostate gland stanza a segment a slice to discover that the Qian turns the cancer focus number and Europe and America close by, so someone think an oriental cancer a growth compare western person slow-moving, clinical case less.Moreover prostate gland cancer and environment are as well relevant to fasten.

【Diagnose 】

The prostate gland cancer start often has no clinical symptom, only bility at check-up the rectum diagnose to discover prostate gland knot stanza.The prostate gland cancer start takes in week outside the prostate gland and easily touch.Wet the Zhu stays with blood in urine probably to have prostate gland to increase to living with companion in the meantime relevant, the cancer causes the row urine difficulty and blood in urine to often belong to a later period.Clinical up have an equal number prostate gland cancer is what prostate gland increases to living the pathologic check of the surgical operation specimen to discover, also have a lot of cases because of transfering symptom to cure.

The diagnosis of the prostate gland cancer has three important points:The ① delivers tumor at first;The ② lymphoid knot transfer;The ③ distance transfer.

(A)deliver tumor rectum to diagnose to discover prostate gland knot stanza at first, can pass tru － cut to live an organization check, or be taken out to absorb a cytology check by the rectum franzen thin needle.Be scanned and can understand swollen thing size and scope by the rectum prostate gland super voice, the normal prostate gland echo is even and the boundary isn't pure while invading and wrapping a film.Echo change may also because of burning disease and stone calculus with the result that, should to discriminate.CT, nuclear magnetic resonance(MR) may also understand pathological changes scope and urine bladder, seminal vesicles of tumor and pour a flattering pathological changes.

(Two)lymphoid transfer the lymphoid knot that the prostate gland cancer first infringes upon to shut the bore － chain inside the Ka, actually is shut the lymphoid knot of bore is generally free from invasion.Clinical up often be called lymphoid knot inside the Ka to shut the bore lymphoid knot, Be located on vein seamy side outside the Ka, follow blood vessel inside the Ka to walk to go is most importantly the lymphoid knot is in response to the clearance.

The diagnosis recent years that the lymphoid knot transfer depends on CT and MR, but can't discover small illness cooking stove.Lymphoid build a shadow can discover that 70% ～s 90%ly transfer.But the false feminine gender be higher with false masculine gender, recent years less applied.In addition to Shu the lymphoid close account of improvement of the most worthy diagnosis, then cut off inside Ka outside blood vessel with shut lymphoid knot between bores, Be cent expect to be more accurate, can avoid since go toward clearance Ka blood vessel, shut bore, basin wall, before the Ka lymphoid knot after the lymph result in leak, lymphoid swollen, the legs swollen etc. complications, because of even extensively cleaning up and can't obstruct have already have of proliferation.

(Three)when the distance transfer vein Bi urine to fasten to build a shadow to discover urethra Geng Zu, explain the tumor has already infringed upon seminal vesicles, urine bladder neck and lymphoid knot, also the distance transfer of possibility.

The bone transfer familiar, only next to lymphoid knot.The whole body isotope scans to strengthen but the even slice normally should thought of to be to transfer.The lung x line takes a picture and can discover the lung transfer, often is a lymphoid tube proliferation and knot a stanza form is seldom seen.

The serum acidity phosphoric acid Mao goes up to have something to do with prostate gland cancer transfer, but lacks particularity.The recent years uses to project an immunity measurement and can raise its particularity.The prostate gland acidity phosphoric acid Mao single gram Long antibody, the prostate gland antigen measurement needs to be raised its particularity.The C expects a prostate gland cancer 20% ～s 70% to have acidity phosphoric acid the Mao to go up, there is lymphoid knot transfer also going up, if continuously go up to then affirm a bone to transfer.The serum acidity phosphoric acid Mao, the prostate gland acidity phosphoric acid Mao goes up to after operation descend and prepare better symbol behind.BE wrap the acidity phosphoric acid of the prostate gland cancer Mao in the film is secrete by the prostate gland cell, Be excrete by prostate gland pipe, prostate gland cancer, the cancer cell output acidity phosphoric acid Mao has no pipe to eject or pipe drive the cancer pathological changes Geng Zu, the Mao absorb into the blood circularly, with go to acidity phosphoric acid the Mao go up.

Pass an above check, the prostate gland cancer then and separately expects and the cultural heritage covariance A period has 10% ～s 20% and the B expects 25% and the C expects 25% and the D expects 35% and explain that the half the number above is no longer the pathological changes for limit while discover.The clinical cent expects to be often lower than actual pathological changes scope.

【Cure measure 】

The treatment of prostate gland cancer can is divided into prostate gland to cure for good Shu and project treatment, endocrine treatment and chemistry to cure.Main according to tumor cent expect to choose to use various method.Al period is the prostate gland increases to living surgical operation accidental detection of cancer, the pathological changes limits at the 3 Gao Bei4's visual field in, the most divide good, greatly parts of patient condition stability, about 2/3 don't make a treatment a pathological changes can slow-moving development, only having or so 1% may die in a cancer.Because it after prepare goodly generally doesn't lay claim to go prostate gland to cure for good Shu or project a treatment, endocrine a treatment.Should periodically with diagnose, go a rectum to diagnose and the B super check, the measurement blood acidity phosphoric acid Mao.The A2 expects not to make to cure 35% and can expand, should consider that going prostate gland cures for good or projects a treatment.The B expect the prostate gland cancer should go to cure for good sex prostate gland resection.The B1 expects the most to divide better, surgical operation can discover 5% ～s, 20% has already transfered lymphoid knot and cure for good to after operation have no cancer to exist for 15 years of reach to 50% ～s 70%.The B2 expects to go prostate gland to cure for good Shu and can discover that 50% has already infringed upon seminal vesicles and 25% ～s 35% has lymphoid knot to transfer, didn't transfer lymphoid knot such as the surgical operation and 86% cancer pathological changeses then limit at prostate gland.The B2 expects to cure for good to have no cancer survival 25% for 15 years after the Shu and therefore have assertion to be in the meantime carry on putting to treat.C period the treatment be more difficult, half chambers aring lymphoid to knot has already transfer already, the general C the one who expect to go to cure for good surgical operation has to match with to put to treat or the endocrine treatment, 5 years, existence rate 60% is or so.Exist 30% ～s 36% for 10 years, have no cancer survival 11% for 15 years.The D expects to mainly cure with the emanation, endocrine and chemistry and exist 30% or so for 5 years, discuss various treatment method respectively as follows.

(A)cure for good the sex prostate gland resection mainly is applicable to a prostate gland cancer to limit at the prostate gland in, but have never had already infringed upon seminal vesicles and lymph to knot through cure for good to after operation get to exist over a long period of time.In common use before through the meeting Yin prostate gland resection, the recent years was widespread adoption the prostate gland cancer cured for good Shu after the disgrace bone and the surgical operation complications of the prostate gland cancer have:Impotence, complete urine incontinence, pressure urine incontinence, keep Yang harm.The urethra urine bladder fits together a people narrow moreover have already sliced an eating to dye, the blood bolts to fill, lymphoid dropsy etc. complications.Prostate gland cancer's curing for good the surgical operation death rate of Shu 1% ～s is 5%s.More extensively applied currently of that surgical operation namely"reserve neurotic prostate gland to cure for good Shu".

(Two)project the treatment outside project light upon 80% ～s 90%, the A, B expect the prostate gland cancer can get a control, failure often because of having already transfer, 10% is part project light upon invalid, 25% ～s 30% and have distance to transfer a tie department invalid.The emanation treatment use 70% in 24 months.Have no tumor existence rate B period for 5 years is the tallest is 80%, the C expects to be tallest to have the invasion rectum, urine bladder of the covariance tumor for 56%, basin wall, urethra have no cancer existence over 3 years.Project the treatment can alleviate to transfer a bone pain.

Project the complications of treatment:Impatient stomach and intestines way responds to 30% ～s 40%, often take place in the 4th week, include diarrhea, rectum unwell, in nasty after heavy;BE about 5% as a result stop cure, the chronic stomach and intestines complications keeps intestinal ulcer for chronic diarrhea, narrow with the Lou way have 12%, the Bi urine fastens complications to have urine Pin and lines up urine difficulty, blood in urine.Have a report to may also cause urethra narrow, wet incontinence etc., also have outside Yin and legs anasarca, impotence...etc..

(Three)the prostate gland cell of the endocrine treatment of normal metabolism the function depend on at the male hormone, change into a pair of hydrogens Gao Tong in the prostate gland, 90% of Gao Tong produces from the testicle, 57% of Gao Tong combines to combine globulin, 40% and white egg white to combine for sex steroid in the blood the circulation, only 3% for swim to leave of the function Gao Tong, get into prostate gland cell inside syrup, make it become a pair of hydrogens Gao Tong, later on with is combine by body compound get into cell nucleus, combine to dye quality at the pit of DNA;DNA creation of activate mRNA, change should be a prostate gland cell the password of the egg white, as to it's metabolize extremely important, cell inside the prostate gland trusts male hormone each not same, the cancer cell is mostly trust in male hormone, endocrine the treatment directly cleans male hormone and can repress its growth.The prostate gland is like ex- row cell more, depends on male hormone more and have never divide cancer and pipe cancer often don't depend on male hormone and the endocrine treatment is invalid.The adrenal glands secretes the male plain Xi two Tongs with take off the hydrogen different male plain Tong, the recent years think these male hormone to occurrence and development of prostate gland cancer relate to smallest.

(Four)the testicle excision of the testicle resection can make serum Gao the Tong decline from 500 ngs/dI to a 50 ngs/dl, thus and availably obstructed most dependence male hormone prostate gland the metabolism of the cancer and make the cancer fade away.The empress possible emergence hair of the testicle resection has fever, perspires, impotence etc..

(Five)estrogen regardless natural with synthesize of hormone can pass to hang body sex gland stalk to lower the level of Gao Tong, repress to hang a body to release the Cu sex gland hormone Huang2 Ti3 Hua4's hormone(LH), may also increment the steroid combine globulin, lower synthesize of Gao Tong inside the testicle, increase to hang a body to urge a milk a vegetable to secrete, lower the prostate gland DNA inside the cell to synthesize, in common use already the Xi female Fen monthly 2 mgs of lmg ～ , can make the Gao Tong attain to the Gao level, have complications to the cardiovascular system, the estrogen applies in a row two years above go to Gao to become can't go against.

(Six)the anti- male hormone medicine the main function obstruct male hormone a function at the Ba cell and the DNA which represses prostate gland cell nucleus synthesize.

(Seven)the Cu sex gland release the hormone similar thing(LHRH-A) long-term in great quantities applies LHRH － , the A not only causes Cu sex gland hormone to secrete excessive, on the contrary repress to hang a body to release Cu sex gland hormone, the LHRH － A starts make Leydig cell creation Gao Tong ascension about March ～ May, hereafter descend the ～ can immediately attain to the Gao level on the 28th on the 21th.The medicine's advantage is the side effect is little, have no cardiovascular complications and stop after the medicine testicle function to have and can reply sex.Sometimes can check an ex- row original cancer to the male hormone with it whether dependence, such as the dependence can continue to use medicine or testicle excision.The LHRH-A in common use medicine is a Buserelin, can immediately attain medicine to go to Gao for a month, the recent years is use the effect often slowly releases LHRH － AN and once reach to with the medicine term of validity for a month.

(Eight)chemistry treatment because of prostate gland cancer 70% ～s 80% be or so to depend on male hormone, so have the initiative consideration endocrine to cure, chemistry treatment in common use in the endocrine, project etc. treatment failure hereafter adopt.

In fine, prostate gland cancer of the chemistry treatment be not ideal and the objective tumor fades away 10% ～s 15%, in the center be worth about 6 months and exist time about 8 months.

【The cause of disease learn 】

Prostate gland cell why develop into the reason of the cancer up to now haven't understand.The American report thinks that the cancer gene is the most important factor in 1985.The virus also is a possible cause of disease, the relation of sex hormone and prostate gland cancer is well-known, puberty cut off Fu pill will not take place a prostate gland cancer, repress the male hormone can make the prostate gland cancer remove.Statisticsed puberty sex activity and prostate gland cancer outbreak related, puberty sex hormone's ising excessive is to help a cancer factor.Statistics the certificate prostate gland cancer has household an outbreak to incline to.Think cadmium to metabolize the fat of the prostate gland cancer now in the environment factor and function importance, there is very high one prostate gland cancer outbreak rate in the village in Canadian Alberta, region, cadmium content is as well high in its drinking, worthy of value.

【The pathology change 】

Above 95% is a gland cancer, rest for move to go cell cancer, scale cancer and tumor.The prostate gland cancer takes place from its gland afterbirth and the pipe and often originate an outside week to take.(namely old age hour is increased a rare urethra surroundings gland body to cause atrophic part the oppression)Prostate gland any part can take place a cancer, but great majority the cancer for take changes in the outside week.The prostate gland gland bubble projects alignment toward the on all sides straight line from the urethra of structure, the cancer change the histology difference biggest broke the alignment of gland body.The cell ratings of the prostate gland cancer is very difficult, because the cell difference of dissimilarity organization very big, often divide the most bad cell to represent its biology characteristic with it, the influence prepare behind.The prostate gland cancer is often many focuses and the single knot stanza only has below 10%.

Nerve inside the prostate gland ties to steep with gland close together, so the cancer often invade nerve surroundings cleft most and have above 85%.Proliferation of the prostate gland cancer can branch office department, lymph and blood go three paths.

The prostate gland cancer after steeping from the gland the occurrence often expanded toward urethra direction, the prostate gland bubble film is an importance natural cover, after wearing through to wrap a film to then prepare bad.The later period tumor can infringe upon urethra, urine bladder neck and seminal vesicles and infringe upon the urine bladder triangle area to cause the urethra Geng Zu as well not a few see, generally don't infringe upon rectum.

The lymphoid knot which infringes upon first shuts the bore － chain inside the Ka, is shut the shut of bore bore lymphoid knot is generally free from invasion.The bone transfer is that the most familiar blood line sows to spread, the familiar part is one by one in order the bone, thoracic vertebrae, rib of the pelvis, waist Zhui, .The internal organs transfers into lung, liver, adrenal glands...etc..Die in a prostate gland cancer 25% to there is lung transfer, but clinical up discover that the lung transfers not enough 6%.

Move to go cell cancer and scale cancer<3%, often go to overlay an occurrence up the skin from the move of prostate gland pipe bitter end, can merge with gland cancer.The average outbreak age compares a gland cancer young 10 years old, acidity phosphoric acid Mao often normal, to emanation and endocrine treatment also responded, after prepare worst.

【Prepare behind 】

The D2 expects 50% to die in a prostate gland cancer in 3 years, in 5 years 80% die in a cancer, and in 10 years 90% die in a cancer.

The one who cure to relapse behind of any endocrine, 90% dies in two years.