The risk of mammary glands cancer drive probably exaggerative

This front, say for those individuals which take to have BRCA1 and BRCA2 to mutate gene part, the researcher usually shows a rate with the outside to estimate to contract the risks of mammary glands cancer in its whole life.But in in the near future announce of a research paper, the researcher of American memorial cancer center of the Sloan-Kettering in New York Colin Begg think that this kind of risk is exaggerated probably.Of so exist this kind of leads a high estimate, is because the female probably suffers from a mammary glands cancer of risk not only mutate with gene related allied, and return is closely related with various other dangerous factors.



Elaborate according to the Begg, some relevant BRCA1s and BRCA2 in earlier period mutate outside show a study of rate main concentration at the dangerous household of those mammary glands cancer high hairs, get thus to be up to at the age of 7071% ～s 85%ly and outside show a rate estimate a value.But so of the research is easily subjected to those stipulations of prejudices that may definitely exist and cause people mean a doubt to this kind of accuracies which estimates a value.In order to avoid this kind of prejudice, the recent research beginning adopts an its family member's data data of women who get the mammary glands cancer, these women choose from take population as the basal tumor is easily taken bad an example.That counterplan to a large extent lowered to outside show the estimate data of rate, but the Begg think this kind of method still easily under the influence of prejudice, because of in the tumor easily the outbreak the example, all dangerous factors all already drive excesssive expression.Begg to 8 example is choose at will of, had cancer household mammary glands cancer the sufferer's BRCA1 and BRCA2 of the history to mutate gene to outside show a rate to carry on analytical.These mammary glands cancer sufferer the history top is random at cancer household.The researcher discovers the cancer risk of the different individual its mammary glands' existence show the differences of Zhao.



Before, people think women's appearing to grow to fasten BRCA1 or BRCA2 mutations inside body can completely decide that it contracts the possibility of mammary glands cancer, but currently see come to this to differ with fact very and far.Probably exist a lot of risks which inherit gene to polish factor in fact.The researcher thinks female individual if is authenticate to take or have more obvious mammary glands cancer household history for the cancer gene, so it with have no explicit disease household history of the female individual compare to have a higher mammary glands cancer a risk.