The rectum cancer assistance cures a Chu argument

Unite the treatment cuts off to many clinical sections of the rectum cancer patient be valid, the rectum cancer assistance treatment idea is according to after operation partial the failure rate be higher but put forward.To the rectum cancer which wears deeply bowel wall or lymphoid knot masculine gender patient, cure for good sex surgical operation, the partial surgical operation is behind usually partial failure.The basin chamber relapses with bowel wall gradually of degree directly relevant, lymphoid knot the assignor risk be higher.The Shu handles behind and should separately expect according to the pathology but settle.The treatment accordings to a clinical cent to expect and reserves an anal need before the Shu.
Lend support to a treatment before the Shu
Lent support to a treatment(the majority was to put to treat to unite with whole body chemotherapy) before the Shu to clinical in the patient of the later period conduct and actions a kind of standard of the treatment has already been accept by everyone.Cure probably beneficial aspect to include decrease tumor proliferation and lower a toxicity before the Shu, raised to protect an anus rate because of morely containing oxygen cell to increase emanation sensitivity.
Have a data hint before the Shu unite a treatment and put to treat to compare alone can make pathology separately expect descend adjust.Generally speak, the above impatient toxicity incidence rate of the consociation treatment III degree's ising 15% ～s is 25%s, the pathology completely alleviates the rate as 10% ～s 30%, clinical efficient is 20%s for 10% ～s, the part relapses the rate as 3% ～s 10%.
To clinical the patient can cut off, cure before the Shu should according to the patient's first circumstance, surgical operation can reserve ass Gua invite muscle but settle.To medium the patient in later period suggest that the adoption unites a treatment before the Shu, the surgical operation after add the Shu takes 5 － FUs as basal chemotherapies.Unite the research covariance of treatment to reason logically behind from the Shu, united treatment before the Shu even better than putting to treat alone, however, whether united a treatment before the Shu more pure put to treat to more effectively then need a further research before the Shu.
After Sweden researcher announced a rectum cancer before the Shu short-term and big amount of to put to treat the article that can make partial control rate and survival expect to improve obviously, some physicians all support this kind of to put to treat a project.Although before the Shu put to treat can obviously lower part to relapse(8% is to 2%), 2 year, existence rate of twos has no dissimilarity(82%) and even will study confirmation in the future to will put to treat before the Shu to existence period beneficial, other also important what time also need definitely, this includes an impatient toxicity, protect anus and ass function, living quality etc..For example have a research enunciation:The impatient toxicity is a grain of cell decrease(8%), meeting private parts hurt(29%) and Shu behind fit together a people Lou(12%), Shu behind fit together a people Lou's patient's 80% to need a surgical operation treatment, this among them 11% patient death.Enhance a short distance to put to treat to relate to the incidence rate of the surgical operation complications and the increment of the death rate before the Shu, and this kind of project also can't raise to protect an anus rate.In another ly random experiment, the short distance puts to treat of the research show before the Shu put to treat nervous system damage an incidence rate is 10%.Therefore should more carefully adopt short distance big amount of to put to treat.
The main purpose which puts to treat before the Shu protects ass Gua to invite a muscle.The advantage which puts to treat before the Shu is the physical volume which contracts to deliver tumor at first.When the tumor is located on the position of close dentation line, the physical volume contracts and can make to reserve ass Gua invite the muscle make possible.However if the tumor directly infringed upon Gua to invite a muscle, even acquiring to completely alleviate also can't reserve Gua invite muscle.For put to treat before the Shu a point in dispute of importance most is whether the cent expect descend adjust reservation Gua about the condition of muscle all right already?When the purpose put to treat before the Shu is to protect Gua invite muscle, the put of normal regulations of the suggestion usage treats amount of and technique, this include have another wild project light upon technique, total measure the 45 Gy ～ 50.4 Gies, every time 1.8 Gies.The surgical operation should carry on after putting to treat to complete for 4~8 weeks.Put with short distance to treat dissimilarity, this kind of normal regulations project contains two advantages, one is put to treat of impatient and poisonous side effect reply quick, two is make tumor for cent expect descend adjust to have appropriate time.But should definitely must be to go by a stomach meeting Yin consociation the patient of the excision first.
The Shu lends support to a treatment behind
The most rectum cancer sufferer once experienced surgical operation in the United States, Shu after can get an accurate pathology to separately expect.Though the image learns before the Shu of the progress can promise to by the square choose a case, the Shu put to treat to is still the most in common use method behind.The international cancer research association lends support to a treatment after think the treatment of consociation method the rightness mediumly the patient in later period is a standard Shu.Putting to treat can lower part to relapse a rate, but if plus to take 5 － FUs as the basal chemotherapy can then turn down part to relapse rate about 10% further, it total 5 years, existence rate's comparing increase of pure surgical operation 10% near ～ss is 15%s.
The Shu puts to treat a disadvantageous factor to include to project light upon behind wild inside increased small intestines is shone on scope.If the patient goes by meeting Yin resection, project light upon wild have to include a meeting private parts.
For lowering a rectum cancer part to relapse a rate, very important in the choice top of treatment.
The modern tumor medical science has already consumedly raised to the fine technical importance of the surgical operation and the quality control of understanding.These be the all successful treatment rectums the key of the cancer.However cure with other tumor similar, end observation the index sign still need time to verify, such as partial control rate, existence period, Gua invite muscle of reservation, surgery merger disease and life quality etc..In most stomach and intestines malignant tumors, no matter which it is, grow single adoptions of treatment method(surgical operation, chemotherapy or put to treat) all developped the biggest limit, but latent small of benefit(effect) usually have already been corresponded augmentative poisonous side effect offset.Generally speaking be various treatment consociation applied, will get the best curative effect and the biggest toxicity, push according to this kind, lower curative effect, accompany with lower complications.
The rectum cancer Shu lends support to a choice of cure the project to still exist a controversy behind.If use 5 － FUs alone, so and continuously lose to note is the best.However, take 5 － FUs as basal consociation to cure a project to have same curative effect.The choice which cures a project should consider the acceptance ability of toxicity, patient etc..
New of the consociation cure a way
With normal regulations time inside can give higher put to treat amount of for foundation, some researchers investigate the adoption 2 times puts to treat to add 5 － FUs everyday.Currently, most basins chambers which unite a treatment project to include the 45 Gy ～ 50.4 Gies before the Shus put to treat, 1.8 Gies/time, the vein pushes to go into 5 － FU/CFs or keeps on drop into 5 － FUs in the meantime.Some researchers more a trait of use 5 － FU/MMC treatment anus tube cancers.A new assistance chemotherapy adopts 5 － FU/MTXs, continuously infuse into 5 － FUs to add to put to treat in the meantime later on, and normal regulations 5 － FU/CF contrast, have no better effect.Ba to treatment the medicine,such as C225, ZD1839 and OSI, put to treat to combine together, the new chemotherapy medicine be like Tomudex, UFT/CF, CPT － 11, the Oxaliplatin, eniluracil and Gemcitabine add to put to treat before the Shu of the I/II expect to study under way medium, III period the clinical trial need to be make sure whether these project with take 5 － FUs as a basal chemotherapy project to compare to have advantage more, the member marking thing can help betterly the choice suit the patient whom the assistance unites a treatment.