Our country the prevention and cure strategy of the stomach cancer

Near half century our country agree with stomach cancer prevention and cure study the work gave to biggest pay attention to and the large person of same belief paid to unremittingly make great effort and obtained very great result.But the very urgent mission in earnest inquiried into the strategic problem of the our country future prevention and cure stomach cancer to have become to put in our in front at present.

The review tally up

1.the nation built up three stomach cancer Gao Fa the spot

From the 80's in last century, face a Qu county, Liaoning Chuang river county, Fukien in Shandong long joy the county built up three stomach cancers high discover a field, openned an exhibition the cause of disease, Epidemiology research of Chinese stomach cancer high Wei crowd.Discovered the special features food of some local residents, like salty pork, fish Lou, ferment a sour pancake, and stomach cancer Gao Fa You3 be nearer concern.Confirming vitamin C, E, the carotene of β－ , selenium...etc. is prevent°from stomach cancer of protection factor and the spring onion garlic vegetable is prevent°from stomach cancer of food.Erupt now a high residents stomach mucosa You door in the hair region Luo rod bacteria(Hp) to check a rate obviously increases Gao.The applied pathology, serology, molecular biology's etc.'s technique did a research and prove that the Hp agree with stomach mucosa cell have with the result that mutate a function.These results all is great significance to the prevention Gao Fa Qu's stomach cancer.

2.the earlier period stomach cancer's diagnosis' technique quickly raises, in early days the stomach cancer constitute the comparison was lower

The 70's in last century ushers in the fiber stomach mirror and stomach double contrast to build a shadow technique and brought about an our country stomach cancer to make a diagnosis and give treatment in early days in 70~80's the fever for study.But see from the national scope, the stomach cancer only had 7% ～s of all stomach cancers 8% in early days, some points be engaged in the medical treatment unit of stomach cancer research also only had 10% ～s 15%;Delivered cancer more to have 5% ～s 10% in the stomach cancer in early days;The small cancer(<40 millimeter) has 15% around;Shallow form extensive type also has 15% or so.Our country earlier period the stomach cancer diagnose the technique progress more and quickly, the level be higher, in early days stomach cancer the comparison was lower in all stomach cancer the composing.

Research earlier period stomach cancer process in, by all means contact stomach cancer before the cancer the problem of pathological changes.The our country offended a pass topic a research to make sure through a nation stomach mucosa not the typical model increase rare of 5, namely gland lump type, reborn type, concealed nest type, the ball kind type and bag form type stomach cancer pathological changes before the cancer.

3.the stomach cancer surgery cure a circumstance

From the 50-90's in last century, the stomach cancer surgical operation excision rate, 5 years after particularly curing for good an excision rate river to cure for good, the existence rate all has an obvious exaltation and appease an excision rate basic have no variety, didn't cut off a rate to year by year descend.In 60~70's with 80~90's compare, the percentage variety that stomach resection type haven't big, but lymphoid settle in addition to scope, empress a stage had obvious extension.From cure for good to cut off for 5 years, the existence rate see, raised to°from 19.6% 63.8% for the past 50 year and raise 300% many.Doubtless, this result is along with the age to go forward, stomach cancer disease period advance, surgical operation technique exaltation but acquire.The recent years(90's) statistics 5 year the existence rate is 51%.Its disease period is an earlier period 29%, the II expects 21%, the IIIa is 28%, later period(IIb+IV period) is 22%.Each expect for 5 years, the existence rate distinguishes to 97.8%, 63.0%, 28.0% and below 20.0%, the recent years compares to raise in 50's about 1000%.Then recent years I+the II expect to have 50% around, the IV expects to descend to°from 50% 10% or so, though the latter implemented extension resection, 5 year, the existence rate onlies have 15% ～s 20%.Full certificate the diagnosis had important meaning towards improving curative effect in early days(I+the II expect).

4.stomach cancer molecular biology the research turned into a new stage

The gene research of the our country stomach cancer, start from the 80's in last century, mostly can is divided into three stages.

From the early part of 80's in last century, make use of tumor DNA miscellaneous handed over a technique to obtain stomach cancer cell the NH3 H3 of the conversion cells, and study the N － Ras and the H － Ras gene to order the relation that the mutation converts with cell, put forward our country bowel a type the member model of the stomach cancer, the agree with stomach mucosa pathological changes evolved way and regulation of cancer gene variation in the process to do system analysis;The 80's expects to start behind, follow international advanced level, authenticate gene variation to take place with tumor, development of the relation did a great deal of experiment a research a work.Studied stomach cancer many accumulation and cell cancer of the gene variation to change and the relation of its occurrence development.Conclusion's ising a stomach cancer cancer to change is many genes to unusually accumulate cause of gradually enter sex process, gene change of number, category and way and it the malignant form type be closely related;Expect from the 90's and behind, most scholars agree with stomach cancer many gene variation accumulation the process obtained a consensus.Along with the thorough research of function gene, environment gene, medicine gene, the stomach cancer gene research turned into a new stage, was diagnosis and gene treatment of the earlier period gene of stomach cancer to lay foundation.

The research work of the stomach cancer biology behavior not a few local units carried on stomach cancer to transfer the research of proliferation member level.

The ① lymphoid knot transfer.The DNA different times body and lymphoid knot transfer and it transfers degree to present just related.The ② blood line transfer.