The valid composition garlic that is in the garlic there has been the research data express, vegetable, can induce a person stomach cancer cell to fasten occurrence Diao Wu and divide.But the relevant garlic vegetable come together Mao β (pol β ) a dependent DNA repair function within thoroughfare a research in the DNA, haven't appeared in newspaper a way currently.University of Peking clinical tumor college Tan2 Xiao3 Hui waited to open an exhibition a related research lately.
The pol β is an important DNA repair Mao and translesion to synthesize Mao.Under the normal circumstance, the pol β is finely regulated in 1 to lowerly express level, its Mao the activity be lower, but exist pol β to too much express in various tumors, and the pol β too much express of tumor cell to chemotherapy with put to treat of the sensitivity lower.Therefore look for to come from natural, the living creature live composition of the curative effect accurate and cell-free poisonous side effect with regulate the expression of pol β , to maintenance cell gene set of stability and exaltation tumor cure of the sensitivity have important meaning.
The etc. of Tan2 Xiao3 Hui passes a research detection and the garlic vegetable fastens pol β mRNA and egg white of BGC823 and MGC803 to express level to the person stomach cancer cell and all have the bottom of the obvious time dependence to adjust a function.Should be next to adjust a companion to have Bax, p 21, Bcl － xl, IkB egg white the mRNA express obvious increment with inside the skin cell select choose a vegetable(SelectinE) obviously descend of phenomenon, hint that the garlic vegetable may pass expression level of regulate the tumor cell pol β , increase the Diao Wu of tumor cell and resist tumor to try the sensitivity of .
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