A research manifestation which comes from England, carrying on an examination to a kind of egg white with related cancer in the urine may check to betterly check an urine bladder cancer than the normal regulations urine.British University of London the Soeber doctor of the college waited in the J Natl Cancer Inst(2002, 94 ∶s 1071) to report to tell this research.
Examine a personnel to mainly pass the means of cytology at present, look for the method of excrescent cell to carry on diagnosis to the urine bladder cancer in the urine.The cytology checks to usually easily check to have in great quantities and unusually the high mark of cell to turn tumor, but turn check of tumor a rate to the low mark not high, because of at this period, the amount of excrescent cell is quite a little.The urine bladder mirror check is an urine bladder cancer the gold standard of the diagnosis.However, Stoeber etc. point out, the urine bladder mirror check is to have already created sex operation, and checks expenses Gao and many sufferers who haven't the typical model urine road symptom may unnecessarily accept an urine bladder mirror check.
The new method aim of Stoeber etc. the miniature chromosome egg white is 5(Mcm5) levels in the examination the urine.The Stoeber group ever discovered that the skin cell contained the abnormality expression of this a series protein on the cancer.
The all urine liquid that is in the research sample all accepted cytology an examination.Sufferer the urine road builds shadow and urine bladder mirror to check in staying an urine sample after in 12 hours accept.Examine to have the examination of same particularity to order with Mcm5 examinations in the cytology, Mcm5 examinations than urine the cytology check have more covariance of show the Zhao to learn sensitivity.(73% is to 48%)Limit under the examination of research, in 353 sufferers who express an urine bladder cancer to is similar to symptom, the researcher used Mcm5 examinations to discover 92% urine bladder cancer a beginning hair or relapse a case.However, that report point out, the Mcm5 examination equally has 22% false masculine gender rates.
Stoeber etc. point out that on this kind of accuracy level, should examine means can examine an earlier period urine bladder cancer.Moreover, they say, should examine a method can also use to examine a high mark to turn tumor.The Stoeber say:"this kind of examination means can examine a various stage, various urine bladder tumor which divide degree, even those tumors which is wet cytology to leak to diagnose.This studies the most important result BE, the item's egg white examination can carry out an in early days diagnose of the urine bladder cancer."
Though this research aims at an urine bladder cancer, the Stoeber group discover Mcm5 examination of another advantage:have 12 sufferers in the research drive end diagnosis is prostate gland cancer, they wet to also have go up of Mcm5 in the liquid.
The researcher thinks that the examination's method has already apply at the possibility of examine other type tumors.
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