Friday, 16 May 2008

Cure lung cancer, have operation still don't have operation?

The - Chu argument PET cures the function in the decision in the lung cancer
In the lung cancer clinical work, the patient often asks thus of problem:Doctor, does this disease want to have operation?
This but a great problem.The language which uses economics speak that is have operation of"risk and income" of problem.This text temporary doesn't discuss risk, speak the income problem that the lung cancer have operation."Income" of tumor treatment is greatly part of to mean the patient's long-term existence, master according to the 2003 American chest surgery doctor of lung cancer treatment guidebook, have the lung cancer that lymphoid knot inside the lung transfer to only, after thinking to only have operation and have operation again add the effect of chemotherapy similar;Transfer lung cancer or chest film chamber which there is lymphoid knot outside the lung(the Zong separate) transfer or the distance transfer of patient, what to adopt is the method which puts to treat to add a chemotherapy, then incline toward two extreme -s to want a Yao surgical operation treatment, want Yao Medicine a treatment.Today in globalization, their treatments norm has to the our country same of instruction value.
Can get a hint so:The clinical cent cured an ex- precision expects to cure meaning to the lung cancer important.
So, how make the cent of lung cancer expect a precision?Currently local in general use check means but speech, exist following blemish:① The not accurate ② be not overall.Usually, the patient comes to hospital first skill check-up, and don't say that the check doesn't arrive, to the muscle following deeper part, often incapable is a dint;Secondly use CT or MRI or B super check materiality internal organs, the biggest paththe Zong of one Li rice separate lymphoid knot, the Zong separates a mirror check to have special meaning, because of it of wound(all numb surgical operation), the common people are hard to accept.
Therefore, the clinical cent which spreads at present expects the method to often underrate the actual circumstance of tumor and need a kind of new check method.The positive electron blast-off breaks a layer to be like(PET) now is exactly so a kind of method, 20041st quarter degree, the American clinical tumor academic association(ASCO) takes off fluorine an oxygen glucose positive electron blast-off a calculator CAT scan Shu(the 18 F - FDG - PET) beyond disputely recommendation to apply to the diagnosis of lung cancer to practice medium, showed an important function in the lymph the knot the distance transfer the cent the period the judgment.
The fluorine takes off an oxygen glucose positive electron to shoot a calculator CAT scan the principle of the Shu(the 18 F - FDG - PET) what kind of?Essentially, it is still isotope to develop a technique, but expresses it special because of taking off the oxygen glucose 18 F - FDG to make to show a Zong with the fluorine.We know that the cell cans not get away from a glucose metabolism, the glucose gets into cell is pass cell membrane up of the glucose carry member(the molecules of the glucose transport, GluT) to complete.The 18 F - FDG is similar to the structure of the glucose, is got into cell by"the mistake read", in 6 -s already the sugar arouse under the function of Mao resolve for take off an oxygen glucose - is 6 - P04(the 18 F - FDG - 6 - P04s)s, but because its member structure is after all different with natural glucose, can't be continue to resolve, make use of, then don't participate three Zuis sour circulation.Because of tumor cell metabolism Gao, hence the 18 F - FDG - 6 - P04s sink into in the tumor cell, because of tumor cell metabolism Gao, the 18 F - FDG - 6 - P04s at tumor cell Zong of thick gather to increase Gao, mean by SUV value.The fluorine takes off the oxygen glucose Zong 18 F(F isotope) creation positive electron in the β + the Shuai become, the PET makes use of the light ability that the positive electron produce information and ask for help of a computer reorganization(matrix laws) to come out - and CT image to reorganize by image expression similar.
From the above-mentioned principle, we can see:The PET is a function to scan, the biggest path.2 value must be a lung cancer.Currently, American suggestion doubts to transfer the pathological changes of the cooking stove for the isolation to all PETs, emphasize that needing to live check a pathology confirm.A certain patient but speech, in front and back follow a check, SUV value of the variety has instruction value very much.
Beyond all doubt, the PET expects to diagnose in the cent of lung cancer by 90% sensitivities and the accuracies in monopolize an Ao head.Although, it of the expenses be close to 10000 dollars.BE be like your investment, if occupy insufficiency, dissymmetry to the information, that you make the decision of to ignore sex, not scientific, your investment may lose capital.Because the long-term of the tumor treatment and expenses of expensive, your making the choice of is the most important one step, the disease under medical treatment in possible arrival, are you to believe science?Or miracle?

No comments: