Friday, 16 May 2008

The Chinese stomach cancer research gets an important result

Chinese whole army's digesting a disease graduate school, Chinese Liberation Arm the fourth military surgeon university Fan generation is clear, the etc. of professor Zhang Xue2 Yong experience successively 25 years agree with stomach cancer research, have already investigated currently in keeping with our country the series of the state of the nation research method, the most dangerous in the stomach cancer of before the cancer the serology of the pathological changes, stomach cancer diagnosis, many the medicine bear a medicine related member of gram Long and reorganization stomach cancer vaccine etc., all acquired a series of and important result.
The earlier period stomach cancer of the great majority sufferer almost has no the symptom of particularity and have already been placed in a later period while being a patient to seek medical advice.But in the meantime stomach cancer of the pathological changes develops before the cancer very slow-moving, even can go against.If the ability is tight to monitor before the cancer pathological changes, probably can avoid cancer occurrence.
Which is that the stomach cancer is the most dangerous of before the cancer pathological changes?Topic set the result manifestation which turn a technique to carry on a research through an immunity set, the bowel of stomach mucosa turns to living and the non- typical model increase to living the space which organizes in the stomach last skin to distribute up consistent with stomach cancer height, should consider that the much easier than cancer change.The particularity living creature canning examine in early days for the research marking, the researcher depended on lymphoid cell miscellaneous handed over a technique establishment 28561 stubs miscellaneous handed over lump cell, was discovering "MGAgs stomach cancer antigen" for the very first time at home and abroad.They the agree with stomach cancer contain very high particularity, scarcely express in the normal organization, but high expression in the stomach cancer the organization.More and more of proof express, this kind of new of tumor antigen, there is diagnosis of show the Zhao value, Be turned to dye a confirmation by immunity set, the its histology masculine gender rate Gao useds for at 90% examine stomach cancer serum in of MGAgs, the masculine gender rate can be up to above 70%, ratio currently extensively applied of the same kind method be 15% in height.They return to used for this kind of antigen the spot census of high Wei crowd, show at as a result to have Gao Di Du4 or the community of male MGAgs to examine stomach cancer in the serum and include some earlier period stomach cancers.In addition also discover the sufferer, 5 years of MGAgs masculine gender, the cancer change the rate reach to 30%, but have no MGAgs sufferer few cancer to change.
To cancer cell probably produce of many the medicine bear a medicine problem, the researcher studied the member mechanism of stomach cancer completely and built up for the very first time 4 kinds of resist the cancer medicine bears a medicine of the stomach cancer cells fasten and discovered 3 kinds bear many medicine gene with correspond of expression egg white, and make 1 kind lately bears the medicine member MGrl - the single grams of the Ag Long antibody, can be part of to converse the variety of stomach cancer cell.Recently, they again acquire a great deal of match with McAb of gram Long, success creation antiserum.Be turned a method confirmation by immunity set, the antiserum can effectively combine with mankind stomach cancer organization, this not only reorganized set up of stomach cancer vaccine to provide foundation for the DNA, and more important that vaccine can contribute to the stomach cancer clinical living creature treatment.

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