The urine bladder is located on lower abdomen under, mainly is a collections and mediate urine a liquid.The skin organization belongs to 1 kind to move to go up the skin cell on the urine bladder, usually not function, don't line up urine the shape present square;When the bulge wet, will pull it to keep present a flat even form, like tightly pull of rubber bands sort, but appetite way or skin up of last the skin organization be fixedly constant, with urine bladder inside of move to go to have an obvious dissimilarity up the skin, the urine bladder moves to go up the skin cell is along with polyuria few but change the cell degree of thickness, breadth thin outside form.
In addition to inflammation or stone calculus, the urine bladder may also have the creation of tumor, patient the most familiar symptom has no painful sex blood in urine at this time and have 90% above, some people will have an unidentified body to ease or anemic etc. phenomenon.The category of urine bladder cancer, the most familiar is to move to go up the skin cancer, have above 90%, secondly is the scale form top skin cancer and gland cancer, the comparison is low at 10%.And treatment up, usually mention of chemistry treatment, mainly is aim at to move to go up skin cancer and speech, on the other scale form skin cancer and gland cancer to the chemotherapy respond not and obviously, the effect is also not easily seen.
The urine bladder moves to go the invasion degree that sex top skin cancer depends on cancer cell and can is divided into the form shallow, invasion and transfers sex three major types, and the treatment also expects but has according to its cent different, Be explain as follows respectively:
The move of the first period form shallow goes up the skin cancer:
This period means that the cancer cell hasn't infringed upon a muscle layer.Usually use the tumor which Be canned see without the aid of instruments to the excision by the urethra tumor resection, some haven't go into action or long the tumor of , have to by chemotherapy to thorough treatment and prevention, this type patient doesn't need to use a whole body chemotherapy.
The urine bladder infuses to note a chemotherapy, make use of urine bladder pipe, chemistry medicine infuse into the urine bladder inside, stop over a period of time, hope that the anti-cancer medicine can kill the cancer cell which cut off to wish an exaltation treatment a rate.The medicine started used in 1960, first use is a thiotepa, because the molecular weight is smaller, easy is an urine bladder mucosa absorb, have 15-20% meeting because of anti-cancer medicine go to marrow in, will repress marrow to build blood function, cause a leukocyte to lower, severity hour will result in a septicemia;Have to notice leukocyte number while use, be low have to stop use medicine a period of time at 3000:00, wait a leukocyte to several times reply to use again.Among them, 1/3 of the patients can make use of thiotepa to completely kill cancer cell, another 1/3, can kill parts of cancer cell.It is invalid to the home position cancer of urine bladder, have to change to use BCG(be so called bcg vaccine) to cure.
The Shu infuses once every week behind, continuous on all sides empress;Infuse once monthly again, continuously for 11 months, whole treat the distance as a year, total 15 times.Measures to add for the 30 mgs 30 Cs.C physiology table salt water.Infuse a medicine again to note to place urine bladder for an hour, again make use of solution urine to eject.
Prevent°from effect but talk, if the patient be after cut off the tumor completely done not give a chemotherapy by urethra, in two years, about having the person of three quarter will relapse and relapse a rate very high.If the sufferer has match urine bladder to infuse to note a treatment, then relapse a rate to decline to 47% after two years.Among them, 15% will continue worsen, 8% will infringe upon a muscle layer and 3% will transfer the organ of distance, so the patient still needs to reply to diagnose for three months once each time and the exploitation checks urine and urine bladder mirror to track a check to thoroughly attain prevention purpose.
The second familiar urine bladder infuses to note the medicine as Mitomycin C, the main function represses the oxygen pit carbohydrate nucleic acid of the take off of cell formation, attain a purpose of kill the cancer cell, because the member have great capacity(compare thiotepa greatly), the Mitomycin C which uses a 30 mgs infuses to note, its method with infuse thiotepa similar.
Cure a result:8% contains complete reaction, 25% contains parts of reaction, 20% responded, produce muscle invasion, become the cancer of invasion, having 7% will transfer and then influence life, side effect is, having 15% will produce chemistry bladder inflammation, long-term come down urine bladder constringency bad, even the urine bladder diminish and another 15% will stimulate the skin of genitals surroundings and result in the phenomenon of red rash.
The third turn the medicine medicine as Adriamycin, molecular weight ratio front two all come greatly, notter easy is urine bladder mucosa absorb, notter easy creation whole body the marrow repress, influenced to the leukocyte and can't have a septicemia problem, either.The operation method and front is two kinds of similar.But medicine effect, having a half will completely kill cancer cell and another three cents of a short while partially kills cancer cell.Having 47% in two years after cure would be partial to relapse and 16% that is among them will change into the urine bladder cancer of invasion.
In fine, these three kinds of medicine use effect all like this, but can what to affirm's being a ratio has never infuse to note effective, having never infused a medicine to have 75% will relapse, but already infuse a medicine only three, 40% will relapse, so, the form shallow sex urine bladder cancer of the urine bladder infuse to note a treatment is existence it of meaning.
Issue 2 infringes upon move of sex to go up the skin cancer:
The cancer cell F infringes upon a muscle layer at this time and even wore deeply a muscle layer.If use is usually cut off tumor Shu by urethra, can't cut off the cancer cell clean, suggest that the sufferer accepts the urine bladder resection of wide scope, or projects therapy to come to aggressive treatment.If patient give to cut off urine bladder or project a treatment, didn't plus a chemistry treatment, it five year livability only have 1/3.So, have to match with the whole body anti-cancer medicine treatment to promote a cure rate.
The chemotherapy which infringes upon a sex urine bladder cancer depend on to the medicine opportune moment is divided into before the Shu after chemotherapy and Shu chemotherapy, generally make use of intravenous injection various anti-cancer medicine, often use of the medicine is four kinds of extenders of anti-cancer medicines for the M -VAC , .(M is Methotreate, V is Vinblastine, A is Adriamycin, the C is for Jian3 Xie3 of the Cisplatin)
Chemistry medicine's reason of the treatment before the Shu as follows:
1.The first step has already discovered to have to slightly transfer when the first step diagnose and the surgical operation can't cut off.
2.Can increase treatment effect when the cancer cell hasn't transfered into important tumor.
3.Can't surgical operation or electrotherapy, can make with the chemotherapy first cancer cell the scope contract and wait until can with surgical operation scope, again give surgical operation excision or project a treatment.
4.The Cisplatin can make to project treatment effect more for the sensitive and cure result better
After cure, having more than half patients will there is complete reaction killing cancer cell and have quarter will not discover cancer cell on the focus.But still some weakness, for example the medicine toxicity be bigger, will result in the leukocyte lower, the sufferer can't have enough physical strength to resist a chemotherapy behind of wide scope urine bladder the complications of the resection;Moreover, some people responded to this anti-cancer medicine, cancer cell on the contrary in the middle transfered in this chemotherapy.
Issue 3 transfers move of sex to go up the skin cancer:
Mean cancer cell the F transfers other organs, like lymphatic gland, skeleton...etc..At this time if the usage be been not enough by resection or wide scope urine bladder resection of the urethra tumor, can't effectively control have already transfer of cancer cell or stability condition.Have to consider to give before the Shu at this time and Shu after whole body chemotherapy.
The medicine of the whole body chemotherapy still with the M -VAC mixture usage is lord, effect 60-70% to cancer cell valid, among them, 25% will completely kill cancer cell;But in two years, having 2/3 people will relapse;Having 17% will not discover that the cancer cell relapse within three years.The side effect of this medicine contains the lower of inflammation, leukocyte of mouth cavity mucosa, even septicemia;The other will also be disgusted and vomit etc. symptom.Usually appropriate treatment and adjust of doctor, these symptoms control the preventive.
Conclusion
In spite of is urine bladder cancer or other cancers, treatment empress of track a check can't neglect, suggest you return to diagnose a check to half year for each three months and check through the simple urine liquid and the cytology check and see whether have the phenomenon of blood in urine or cancer cell, can have an urine bladder mirror check when it's necessary, thoroughly control.
Sunday, 18 May 2008
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