Come from the United States and Senegal of the researcher said, although more have the mammary glands cancer marking thing of particularity really certainly makes the person be subjected to a benefit rather many, the form view genetics marking the thing(for example A Ji turn of DNA sequence) probably can let mammary glands cancer the examination is no longer depend on in Mu Ba to shoot a slice.
90's in last century, made use of mammary glands to build a shadow to carry on to diagnose in early days, urged the mammary glands cancer show of death rate Zhao to descend to some extent.But currently, the mammary glands cancer is still the female's second cancer cutthroat.
Because the Mu Ba shoot a slice of check also can't go in the developing country, so have to design a new mammary glands cancer examination method.
Is the south from University of Washington in Seattle rare? Together Wei studied blood the value of the thing in the different living creature marking with her colleagues especially.They carried on a research to 93 blood plasma samples with not- female(have another for the mammary glands cancer in later period) west, with 76 healthily artificial matched controls, turn an examination through a high flux DNA A Ji, made sure following four kinds of candidate for election geneses of the A Ji turn excrescent frequency:APC, GSTP1, the Rass1 AN and RAR-beta-2.
The research group is divided into sample equally the training gather to gather with verification, they discover the APC of sufferer's team, GSTP1 and the A Ji within DNA of the Rass1 A blood plasma turn frequency far high is 17% respectively at the matched control: 0%, 26%: 0%, 32%: 5%.
Compare under, sufferer's team and the A Ji of the matched control RAR-beta-2 turn frequency difference not to have covariance to show Zhao, is 26%:8%.
Group report call that at least a kind of A Ji of gene that can confirm a cancer case's turning an intelligent degree is 62%, the particularity is 87%.There is 8 earlier period mammary glands cancer in the test being checked.(total 24 have 33%)
It writes a way in the report:" Different form view genetics marking thing, the combination useds for the examination which incubates circulating tumor cell, may make us go deep into a ground of understanding human body more to deliver the living creature behavior of sex tumor at first, and acquire worthy prepare behind information, easy to disease period supervision."
The researchers still add a way:"Can what to foresee BE, other related, the repressor gene of the particularity tumor will also enlarge this marking thing combination medium with raise the intelligent degree of examination.This for mammary glands cancer of the earlier period diagnose particularly is valid."
Reference:《Clinical tumor in the United States learns a magazine 》 J Clin Oncol 2006; 24: 4262-4269
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